Clomiphene is an active ingredient used in the hormonal treatment of women who want to have children. Clomiphene is said to stimulate egg production on the one hand and ovulation on the other. Here you can read how Clomiphene works and what chances of success the treatment has.
When is clomiphene used?
For some women, ovulation occurs irregularly or not at all, making it difficult for them to get pregnant.
In such cases, the use of the drug clomiphene has proven. The active ingredient improves a woman’s fertility by positively influencing her hormonal balance. Clomiphene is popular not only because of its ease of use but also because it has few side effects and still achieves good results.
How does clomiphene affect hormonal balance?
Clomiphene is an anti-estrogen, an active ingredient that simulates a lack of estrogens in the female body. To compensate this lack of estrogen, hormones are released via the pituitary gland. The membrane-stimulating hormone (FSH) stimulates the ovaries and more eggs, and therefore more estrogen is produced. Luteinizing Hormone (LH) stimulates ovulation.
For the next 12 to 24 hours after taking clomiphene, there is an increased chance that a mature egg cell will be fertilized.
How does clomiphene treatment work?
Clomiphene is mostly prescribed in the form of tablets because the treatment can be carried out easily from home. The dosage is set individually by the attending doctor but is usually 25 to 50 milligrams per tablet, one of which is taken daily.
Between the third and fifth day of the cycle, calculated from the onset of the period, the treatment begins and you take one tablet for five days in a row. If hormone therapy works well, ovulation should occur about a week after the last dose. If there are no ovulation 20 days after the last dose, treatment is repeated in the next cycle.
Your doctor will check the maturation of the eggs in several ultrasound examinations during the treatment. In this way, he can see how many egg blisters develop and whether ovulation actually occurs. Some blood is drawn in each cycle to measure changes in the hormonal balance.
Each body responds individually to the treatment and sometimes it takes some time for hormone therapy to work. For most patients, a maximum of six cycles is supported with clomiphene, since the chances of success tend to decrease afterward. If the therapy does not work for you, there are other fertility-promoting preparations and methods that may bring you closer to your desire to have children. Your doctor will advise you in detail on this.