Pregabalin, marketed under the brand Lyrica, is used for the treatment of neuropathic pain. This pain may result due to spinal injury, post-herpetic pain, fibromyalgia, diabetes, and generalized and social anxiety as well. It is also used by individuals suffering from pain due to restless leg syndrome, pruritis, and chemotherapy.
Pregabalin developed as a successor to gabapentin and is an anticonvulsant drug. According to preclinical studies on anticonvulsant activity, pregabalin is known to be 3-4 times more effective than gabapentin. In fact, it works by reducing the excessive excitation of the nerves by binding to the calcium channels of the neurons of the brain.
By inhibiting the calcium channels it decreases the neurotransmitters released in the CNS. As a result of which pregabalin imparts pain relief, anti-anxiety, and anti-seizure effects. However, it is not narcotic in nature.
Pregabalin has been found to be highly effective in pain management in patients suffering from pain due to nerve damage disorders like diabetic neuropathy, spinal cord injury, chemotherapy-induced pain, and chronic back pain.
It is given orally and is available as 50, 75, 100, 150, 200, 225 and 300 mg capsule. The maximum dose is 300 to 600 mg depending on the conditions.
Side Effects Of Pregabalin :
Pregabalin has mild to moderate side effects depending on its dose and duration of the course, but it is generally well tolerated.
Contact a doctor or go to an ER immediately if you notice any signs of allergic reactions such as swelling of face, mouth, throat, trouble breathing, rashes, hives. Also, any of the unusual side effects must not be ignored.